ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2318-100

Price for BNCB2318-100

Size / count 1x 100 µL

About this product

Recognizes a protein of 110 kDa, identified as Excision Repair Cross Complementing 1 (ERCC1) . It is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae, which is required in mitotic intrachromosomal recombination and repair. ERCC1 is required in repair of cisplatin-induced DNA adducts and ultraviolet (UV) -induced DNA damage. High expression of ERCC1 has been linked to tumor progression in a variety of cancers including non-small cell lung cancer (NSCLC), squamous cell carcinoma of the head, ovarian cancer and esophageal cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB2318-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: COFS4; DNA excision repair protein ERCC1; ERCC1; Excision repair cross complementing 1; RAD10; UV20
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ERCC1
Gene ID: 2067
NCBI Gene ID: 435981
UniProt: P07992
Swiss Prot: P07992
Host: Mouse
Species Reactivity: Human
Reactivity: ERCC1|RAD10
Immunogen: Recombinant fragment (around aa 191-281) of human ERCC1 protein (exact sequence is proprietary)
Target Antigen: ERCC1 | RAD10
Clonality: Monoclonal
Clone: ERCC1/2318
Type: Primary
Source: Animal
Origin: Animal
Positive Control: HeLa, HepG2 cells. Tonsil or Prostate.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: ~110 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), Biotin conjugate, 0.1mg/mL?

The catalog number for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), Biotin conjugate, 0.1mg/mL is BNCB2318-100.

What sizes are available for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), Biotin conjugate, 0.1mg/mL?

ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), Biotin conjugate, 0.1mg/mL in stock?

ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), Biotin conjugate, 0.1mg/mL?

ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), Biotin conjugate, 0.1mg/mL?

The safety data sheet for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), Biotin conjugate, 0.1mg/mL used for?

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.