ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), 0.2mg/mL

Catalog number BNUB2318-100

Price for BNUB2318-100

Size / count 1x 100 µL

About this product

Recognizes a protein of 110 kDa, identified as Excision Repair Cross Complementing 1 (ERCC1) . It is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae, which is required in mitotic intrachromosomal recombination and repair. ERCC1 is required in repair of cisplatin-induced DNA adducts and ultraviolet (UV) -induced DNA damage. High expression of ERCC1 has been linked to tumor progression in a variety of cancers including non-small cell lung cancer (NSCLC), squamous cell carcinoma of the head, ovarian cancer and esophageal cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB2318-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: COFS4; DNA excision repair protein ERCC1; ERCC1; Excision repair cross complementing 1; RAD10; UV20
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ERCC1
Gene ID: 2067
NCBI Gene ID: 435981
UniProt: P07992
Swiss Prot: P07992
Host: Mouse
Species Reactivity: Human
Reactivity: ERCC1|RAD10
Immunogen: Recombinant fragment (around aa 191-281) of human ERCC1 protein (exact sequence is proprietary)
Target Antigen: ERCC1 | RAD10
Clonality: Monoclonal
Clone: ERCC1/2318
Type: Primary
Source: Animal
Origin: Animal
Positive Control: HeLa, HepG2 cells. Tonsil or Prostate.
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: ~110 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), 0.2mg/mL?

The catalog number for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), 0.2mg/mL is BNUB2318-100.

What sizes are available for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), 0.2mg/mL?

ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), 0.2mg/mL in stock?

ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), 0.2mg/mL?

ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), 0.2mg/mL?

Estimated delivery time for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), 0.2mg/mL?

The safety data sheet for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e100892/msds/bnub2318-100.pdf.

What is ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), 0.2mg/mL used for?

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.