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Product details
Catalog number BNCB2362-500
Price for BNCB2362-500
Size / count 1x 500 µL
This MAb recognizes a protein of 65 kDa, which is identified as glutamic acid decarboxylase 2 (GDA2) . It is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. There are two forms of glutamic acid decarboxylases (GAD's) that are found in the brain: GAD2 (also known as GAD65) and GAD1 (also known as GAD67) . GAD1 and GAD2 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate-limiting step in the production of GABA (-aminobutyric acid) from L-glutamic acid. Although both GAD's are found in the brain, GAD2 localizes to synaptic vesicle membranes in nerve terminals, while GAD1 is distributed throughout the cell. A pathogenic role for GAD2 is identified in the human pancreas since it has been identified as an autoantibody and an auto-reactive T cell target in insulin-dependent diabetes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for GAD2 / GAD65 (GABAergic Neuronal Marker) (GAD2/2362), Biotin conjugate, 0.1mg/mL is BNCB2362-500.
GAD2 / GAD65 (GABAergic Neuronal Marker) (GAD2/2362), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
GAD2 / GAD65 (GABAergic Neuronal Marker) (GAD2/2362), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
GAD2 / GAD65 (GABAergic Neuronal Marker) (GAD2/2362), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for GAD2 / GAD65 (GABAergic Neuronal Marker) (GAD2/2362), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for GAD2 / GAD65 (GABAergic Neuronal Marker) (GAD2/2362), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0296061270361e100058/msds/bncb2362-500.pdf.
This MAb recognizes a protein of 65 kDa, which is identified as glutamic acid decarboxylase 2 (GDA2) . It is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. There are two forms of glutamic acid decarboxylases (GAD's) that are found in the brain: GAD2 (also
Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.
A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.
Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.
