• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein) (BCMA/2366), 1mg/mL

Catalog number BNUM2366-50

Price for BNUM2366-50

Sign In for Pricing

Size / count 1x 50 µL

About this product

The B cell maturation protein (BCMA) is a type I integral membrane protein that belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is expressed as a 184 amino acid peptide that is expressed only in mature B-lymphocytes and is located on the cis part of the Golgi apparatus. BCMA shares significant homology with TACI (transmembrane activator) within the cysteine-rich domain. TACI has been shown to bind CAML, which induces activation of NFAT (nuclear factor of activated T cells) . Both BCMA and TACI have been shown to bind APRIL and TALL-1, which stimulate B cell proliferation in conjunction with other B-cell activators. When overexpressed, TALL-1 stimulates the development of systemic lupus erythaematosus (SLE) .Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM2366-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
B-cell maturation protein; BCMA; CD269; TNR17; Tumor necrosis factor receptor superfamily member 17 (TNFRSF17)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD269
Gene ID
608
NCBI Gene ID
2556
UniProt
Q02223
Swiss Prot
Q02223
Host
Mouse
Species Reactivity
Human
Reactivity
BCMA|CD269|TNFRSF17
Immunogen
Recombinant human CD269 protein fragment (around aa 78-184) (exact sequence is proprietary)
Target Antigen
BCMA | CD269 | TNFRSF17
Clonality
Monoclonal
Clone
BCMA/2366
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Autoimmunity, Immunology
Positive Control
NAMALWA Cells. Tonsil. Gastric Carcinoma
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
20 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein) (BCMA/2366), 1mg/mL?

The catalog number for CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein) (BCMA/2366), 1mg/mL is BNUM2366-50.

What sizes are available for CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein) (BCMA/2366), 1mg/mL?

CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein) (BCMA/2366), 1mg/mL is available in the following size(s): 1x 50 µL.

Is CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein) (BCMA/2366), 1mg/mL in stock?

CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein) (BCMA/2366), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein) (BCMA/2366), 1mg/mL?

CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein) (BCMA/2366), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein) (BCMA/2366), 1mg/mL?

Estimated delivery time for CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein) (BCMA/2366), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein) (BCMA/2366), 1mg/mL?

The safety data sheet for CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein) (BCMA/2366), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD269 / TNFRSF17 / BCMA (B-Cell Maturation Protein) (BCMA/2366), 1mg/mL used for?

The B cell maturation protein (BCMA) is a type I integral membrane protein that belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is expressed as a 184 amino acid peptide that is expressed only in mature B-lymphocytes and is located on the cis part of the Golgi apparatus. BCMA sh

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

You Might Also Like
CD4 (EDU-2), CF405S conjugate, 0.1mg/mL
CD4 (EDU-2), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040345-100
CD3e (CRIS-7), CF640R conjugate, 0.1mg/mL
CD3e (CRIS-7), CF640R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC401050-500
CD63 (MX-49.129.5), CF405S conjugate, 0.1mg/mL
CD63 (MX-49.129.5), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040525-500
CD54 / ICAM-1 (15.2), CF568 conjugate, 0.1mg/mL
CD54 / ICAM-1 (15.2), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC682853-500
HLA-Aw32 & HLA-A25 (MHC I) (CATA-1), CF647 conjugate, 0.1mg/mL
HLA-Aw32 & HLA-A25 (MHC I) (CATA-1), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC471073-100
TGF-beta (1D11.16.8), CF568 conjugate, 0.1mg/mL
TGF-beta (1D11.16.8), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680977-100
CD3e (B-B12), CF647 conjugate, 0.1mg/mL
CD3e (B-B12), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC471052-500
CD106 / VCAM1 (B-K9), CF594 conjugate, 0.1mg/mL
CD106 / VCAM1 (B-K9), CF594 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC940304-100