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Product details

SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) (SDHB/2382), CF594 conjugate, 0.1mg/mL

Catalog number BNC942382-500

Price for BNC942382-500

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Size / count 1x 500 µL

About this product

Succinate dehydrogenase (SDH) is Complex II in the mitochondria, vital for mitochondrial electron transport, as well as Krebs cycle function. Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA), an iron-sulfur protein (SDHB) and two membrane-bound subunits (SDHC and SDHD) anchored to the inner mitochondrial membrane. The SDH complex functions as a tumor suppressor. Loss of any subunit proteins lead to destabilization of the complex and tumor formation. Antibody to SDHB is helpful in the identification of phaeochromocytomas, paragangliomas and GIST. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC942382-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CWS2; DHSB; Iron-sulfur subunit of complex II; PGL4; SDH2; SDHB; SDHIP; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit; mitochondrial; Succinate Dehydrogenase Complex Subunit B Iron Sulfur Protein
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
SDHB
Gene ID
6390
NCBI Gene ID
465924
UniProt
P21912
Swiss Prot
P21912
Host
Mouse
Species Reactivity
Human
Reactivity
SDHB
Immunogen
Recombinant fragment (around aa 165-273) of human SDHB protein (exact sequence is proprietary)
Target Antigen
SDHB
Clonality
Monoclonal
Clone
SDHB/2382
Type
Primary
Source
Animal
Origin
Animal
Positive Control
Jurkat or HepG2 cells. Human kidney or liver.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
32 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) (SDHB/2382), CF594 conjugate, 0.1mg/mL?

The catalog number for SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) (SDHB/2382), CF594 conjugate, 0.1mg/mL is BNC942382-500.

What sizes are available for SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) (SDHB/2382), CF594 conjugate, 0.1mg/mL?

SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) (SDHB/2382), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) (SDHB/2382), CF594 conjugate, 0.1mg/mL in stock?

SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) (SDHB/2382), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) (SDHB/2382), CF594 conjugate, 0.1mg/mL?

SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) (SDHB/2382), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) (SDHB/2382), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) (SDHB/2382), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) (SDHB/2382), CF594 conjugate, 0.1mg/mL?

The safety data sheet for SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) (SDHB/2382), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) (SDHB/2382), CF594 conjugate, 0.1mg/mL used for?

Succinate dehydrogenase (SDH) is Complex II in the mitochondria, vital for mitochondrial electron transport, as well as Krebs cycle function. Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA), an iron-sulfur protein (SDHB) and two membrane-bound subunits (SDHC and SDHD) an

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

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