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Product details

CD25 / IL2RA (Activated Lymphocyte Marker) (IL2RA/2394), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2394-500

Price for BNCB2394-500

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Size / count 1x 500 µL

About this product

Recognizes a protein of 55 kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkin's disease, HTLV-1 adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB2394-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
IL2 Receptor alpha; IL2R alpha chain; IL2R; IL2R subunit alpha IL2RA; Interleukin-2 receptor subunit alpha; Ly43; p55; p55 chain; T Cell Growth Factor Receptor; TAC antigen; TCGFR
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IL2RA
Gene ID
3559
NCBI Gene ID
231367
UniProt
P01589
Swiss Prot
P01589
Host
Mouse
Species Reactivity
Human
Reactivity
CD25|IL2RA
Immunogen
Recombinant human IL2RA protein fragment (around aa 42-183) (exact sequence is proprietary)
Target Antigen
CD25 | IL2RA
Clonality
Monoclonal
Clone
IL2RA/2394
Type
Primary
Source
Animal
Origin
Animal
Positive Control
PHA-stimulated human lymphocytes. Human lymph node or tonsil.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
55 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for CD25 / IL2RA (Activated Lymphocyte Marker) (IL2RA/2394), Biotin conjugate, 0.1mg/mL?

The catalog number for CD25 / IL2RA (Activated Lymphocyte Marker) (IL2RA/2394), Biotin conjugate, 0.1mg/mL is BNCB2394-500.

What sizes are available for CD25 / IL2RA (Activated Lymphocyte Marker) (IL2RA/2394), Biotin conjugate, 0.1mg/mL?

CD25 / IL2RA (Activated Lymphocyte Marker) (IL2RA/2394), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD25 / IL2RA (Activated Lymphocyte Marker) (IL2RA/2394), Biotin conjugate, 0.1mg/mL in stock?

CD25 / IL2RA (Activated Lymphocyte Marker) (IL2RA/2394), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD25 / IL2RA (Activated Lymphocyte Marker) (IL2RA/2394), Biotin conjugate, 0.1mg/mL?

CD25 / IL2RA (Activated Lymphocyte Marker) (IL2RA/2394), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD25 / IL2RA (Activated Lymphocyte Marker) (IL2RA/2394), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for CD25 / IL2RA (Activated Lymphocyte Marker) (IL2RA/2394), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD25 / IL2RA (Activated Lymphocyte Marker) (IL2RA/2394), Biotin conjugate, 0.1mg/mL?

The safety data sheet for CD25 / IL2RA (Activated Lymphocyte Marker) (IL2RA/2394), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD25 / IL2RA (Activated Lymphocyte Marker) (IL2RA/2394), Biotin conjugate, 0.1mg/mL used for?

Recognizes a protein of 55 kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkin's disease, HTLV-1 adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. In

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

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