MDM2 (MDM2/2414), CF647 conjugate, 0.1mg/mL

Catalog number BNC472414-100

Price for BNC472414-100

Size / count 1x 100 µL

About this product

MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. Overexpression of MDM2 protein is detected in a variety of cancers. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472414-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ACTFS; Double minute 2 protein; E3 ubiquitin-protein ligase; Hdm2; HDMX; MDM2; MDM2 oncogene E3 ubiquitin protein ligase; MDM2BP; Mouse Double Minute 2; MTBP; Murine Double Minute Chromosome 2; p53 Binding Protein Mdm2; p53-binding protein Mdm2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MDM2
Gene ID: 4193
NCBI Gene ID: 484551
UniProt: Q00987
Swiss Prot: Q00987
Host: Mouse
Species Reactivity: Human
Reactivity: MDM2
Immunogen: Recombinant human MDM2 protein fragment (around aa 126-254) (exact sequence is proprietary)
Target Antigen: MDM2
Clonality: Monoclonal
Clone: MDM2/2414
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: A549 or HeLa cells. Pancreas.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 90 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for MDM2 (MDM2/2414), CF647 conjugate, 0.1mg/mL?

The catalog number for MDM2 (MDM2/2414), CF647 conjugate, 0.1mg/mL is BNC472414-100.

What sizes are available for MDM2 (MDM2/2414), CF647 conjugate, 0.1mg/mL?

MDM2 (MDM2/2414), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MDM2 (MDM2/2414), CF647 conjugate, 0.1mg/mL in stock?

MDM2 (MDM2/2414), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MDM2 (MDM2/2414), CF647 conjugate, 0.1mg/mL?

MDM2 (MDM2/2414), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MDM2 (MDM2/2414), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for MDM2 (MDM2/2414), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MDM2 (MDM2/2414), CF647 conjugate, 0.1mg/mL?

The safety data sheet for MDM2 (MDM2/2414), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b7061270361e10bcf9/msds/bnc472414-100.pdf.

What is MDM2 (MDM2/2414), CF647 conjugate, 0.1mg/mL used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.