MDM2 (MDM2/2414), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2414-100

Price for BNCB2414-100

Size / count 1x 100 µL

About this product

MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. Overexpression of MDM2 protein is detected in a variety of cancers. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB2414-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ACTFS; Double minute 2 protein; E3 ubiquitin-protein ligase; Hdm2; HDMX; MDM2; MDM2 oncogene E3 ubiquitin protein ligase; MDM2BP; Mouse Double Minute 2; MTBP; Murine Double Minute Chromosome 2; p53 Binding Protein Mdm2; p53-binding protein Mdm2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MDM2
Gene ID: 4193
NCBI Gene ID: 484551
UniProt: Q00987
Swiss Prot: Q00987
Host: Mouse
Species Reactivity: Human
Reactivity: MDM2
Immunogen: Recombinant human MDM2 protein fragment (around aa 126-254) (exact sequence is proprietary)
Target Antigen: MDM2
Clonality: Monoclonal
Clone: MDM2/2414
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: A549 or HeLa cells. Pancreas.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 90 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for MDM2 (MDM2/2414), Biotin conjugate, 0.1mg/mL?

The catalog number for MDM2 (MDM2/2414), Biotin conjugate, 0.1mg/mL is BNCB2414-100.

What sizes are available for MDM2 (MDM2/2414), Biotin conjugate, 0.1mg/mL?

MDM2 (MDM2/2414), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MDM2 (MDM2/2414), Biotin conjugate, 0.1mg/mL in stock?

MDM2 (MDM2/2414), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MDM2 (MDM2/2414), Biotin conjugate, 0.1mg/mL?

MDM2 (MDM2/2414), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MDM2 (MDM2/2414), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for MDM2 (MDM2/2414), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MDM2 (MDM2/2414), Biotin conjugate, 0.1mg/mL?

The safety data sheet for MDM2 (MDM2/2414), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MDM2 (MDM2/2414), Biotin conjugate, 0.1mg/mL used for?

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.