BOB.1 (B-Cell Marker) (BOB1/2421), 1mg/mL

Catalog number BNUM2421-50

Price for BNUM2421-50

Size / count 1x 50 µL

About this product

BOB-1 is a transcriptional coactivator that specifically associates with either POU2F1/OCT1 or POU2F2/OCT2, boosting the promoter activity of those complexes. It is essential for the response of B-cells to antigens, required for the formation of germinal centers, and regilates IL-6 expression. BOB-1 expression in a variety of established B-cell lines, representing different stages of B-cell development, has suggested a constitutive, B-cell-specific expression pattern. LP cells in nodular lymphocyte predominant Hodgkin lymphoma, because they are germinal center-derived, are consistently immuno-positive for BOB-1. Conversely, only some cases of classical Hodgkin lymphoma show BOB-1 immuno-reactivity within the Hodgkin and Reed-Sternberg cells. Expression of BOB-1 has been reported in follicular center cell lymphoma, diffuse large B-cell lymphoma and some cases of acute myeloid leukemia. B-CLL, marginal zone lymphoma, and mantle cell lymphoma may show weak to moderate immunoreactivity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUM2421-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BOB-1; B-cell-specific coactivator OBF-1; OCT-binding factor 1; POU domain class 2-associating factor 1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: POU2AF1
Gene ID: 5450
NCBI Gene ID: 654525
UniProt: Q16633
Swiss Prot: Q16633
Host: Mouse
Species Reactivity: Human
Reactivity: BOB.1
Immunogen: Recombinant fragment (around aa 148-255) of human BOB1 (POU2AF1) protein (exact sequence is proprietary)
Target Antigen: BOB.1
Clonality: Monoclonal
Clone: BOB1/2421
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer, Immunology
Positive Control: Raji, Ramos cells. Spleen or Tonsil.
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: 35 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse)
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Frequently Asked Questions

What is the catalog number for BOB.1 (B-Cell Marker) (BOB1/2421), 1mg/mL?

The catalog number for BOB.1 (B-Cell Marker) (BOB1/2421), 1mg/mL is BNUM2421-50.

What sizes are available for BOB.1 (B-Cell Marker) (BOB1/2421), 1mg/mL?

BOB.1 (B-Cell Marker) (BOB1/2421), 1mg/mL is available in the following size(s): 1x 50 µL.

Is BOB.1 (B-Cell Marker) (BOB1/2421), 1mg/mL in stock?

BOB.1 (B-Cell Marker) (BOB1/2421), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BOB.1 (B-Cell Marker) (BOB1/2421), 1mg/mL?

BOB.1 (B-Cell Marker) (BOB1/2421), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for BOB.1 (B-Cell Marker) (BOB1/2421), 1mg/mL?

Estimated delivery time for BOB.1 (B-Cell Marker) (BOB1/2421), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for BOB.1 (B-Cell Marker) (BOB1/2421), 1mg/mL?

The safety data sheet for BOB.1 (B-Cell Marker) (BOB1/2421), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is BOB.1 (B-Cell Marker) (BOB1/2421), 1mg/mL used for?

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.