Product details
Catalog number BNC882426-500
Price for BNC882426-500
Size / count 1x 500 µL
ZFYVE28 belongs to the lst-2 family. It contains 1 FYVE-type zinc finger. The FYVE-type zinc finger mediates the interaction with phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes when not mono-ubiquitinated at Lys-87. Mono-ubiquitination at Lys-87 prevents binding to phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes. ZFYVE28 is a negative regulator of epidermal growth factor receptor (EGFR) signaling. It acts by promoting EGFR degradation in endosomes when not mono-ubiquitinated. The FYVE domain has been identified in a number of unrelated signaling molecules. This protein functions to recruit SMAD2 to the transforming growth factor-beta receptor. The FYVE domain is required to maintain the normal localization of this protein but is not involved in mediating interaction with SMADs. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF488A conjugate, 0.1mg/mL is BNC882426-500.
ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
ZFYVE28 belongs to the lst-2 family. It contains 1 FYVE-type zinc finger. The FYVE-type zinc finger mediates the interaction with phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes when not mono-ubiquitinated at Lys-87. Mono-ubiquitination at Lys-87 prevents binding
A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.
Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.
Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.