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Product details

ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF594 conjugate, 0.1mg/mL

Catalog number BNC942426-500

Price for BNC942426-500

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Size / count 1x 500 µL

About this product

ZFYVE28 belongs to the lst-2 family. It contains 1 FYVE-type zinc finger. The FYVE-type zinc finger mediates the interaction with phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes when not mono-ubiquitinated at Lys-87. Mono-ubiquitination at Lys-87 prevents binding to phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes. ZFYVE28 is a negative regulator of epidermal growth factor receptor (EGFR) signaling. It acts by promoting EGFR degradation in endosomes when not mono-ubiquitinated. The FYVE domain has been identified in a number of unrelated signaling molecules. This protein functions to recruit SMAD2 to the transforming growth factor-beta receptor. The FYVE domain is required to maintain the normal localization of this protein but is not involved in mediating interaction with SMADs. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC942426-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Lateral signaling target protein 2 homolog; LST2; LYST2; Zinc finger FYVE domain-containing protein 28 (ZFYVE28)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ZFYVE28
Gene ID
57732
NCBI Gene ID
292056
UniProt
Q9H9
Swiss Prot
Q9H9
Host
Mouse
Species Reactivity
Human
Reactivity
ZFYVE28
Immunogen
Recombinant full-length human ZFYVE28 protein
Target Antigen
ZFYVE28
Clonality
Monoclonal
Clone
LST2/2426
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
PC3 cells. Testis, Brain, Colon, Kidney or Stomach.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
96 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF594 conjugate, 0.1mg/mL?

The catalog number for ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF594 conjugate, 0.1mg/mL is BNC942426-500.

What sizes are available for ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF594 conjugate, 0.1mg/mL?

ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF594 conjugate, 0.1mg/mL in stock?

ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF594 conjugate, 0.1mg/mL?

ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF594 conjugate, 0.1mg/mL?

The safety data sheet for ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), CF594 conjugate, 0.1mg/mL used for?

ZFYVE28 belongs to the lst-2 family. It contains 1 FYVE-type zinc finger. The FYVE-type zinc finger mediates the interaction with phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes when not mono-ubiquitinated at Lys-87. Mono-ubiquitination at Lys-87 prevents binding

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

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