ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2426-500

Price for BNCB2426-500

Size / count 1x 500 µL

About this product

ZFYVE28 belongs to the lst-2 family. It contains 1 FYVE-type zinc finger. The FYVE-type zinc finger mediates the interaction with phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes when not mono-ubiquitinated at Lys-87. Mono-ubiquitination at Lys-87 prevents binding to phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes. ZFYVE28 is a negative regulator of epidermal growth factor receptor (EGFR) signaling. It acts by promoting EGFR degradation in endosomes when not mono-ubiquitinated. The FYVE domain has been identified in a number of unrelated signaling molecules. This protein functions to recruit SMAD2 to the transforming growth factor-beta receptor. The FYVE domain is required to maintain the normal localization of this protein but is not involved in mediating interaction with SMADs. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB2426-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Lateral signaling target protein 2 homolog; LST2; LYST2; Zinc finger FYVE domain-containing protein 28 (ZFYVE28)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ZFYVE28
Gene ID: 57732
NCBI Gene ID: 292056
UniProt: Q9H9
Swiss Prot: Q9H9
Host: Mouse
Species Reactivity: Human
Reactivity: ZFYVE28
Immunogen: Recombinant full-length human ZFYVE28 protein
Target Antigen: ZFYVE28
Clonality: Monoclonal
Clone: LST2/2426
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: PC3 cells. Testis, Brain, Colon, Kidney or Stomach.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 96 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), Biotin conjugate, 0.1mg/mL?

The catalog number for ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), Biotin conjugate, 0.1mg/mL is BNCB2426-500.

What sizes are available for ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), Biotin conjugate, 0.1mg/mL?

ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), Biotin conjugate, 0.1mg/mL in stock?

ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), Biotin conjugate, 0.1mg/mL?

ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), Biotin conjugate, 0.1mg/mL?

The safety data sheet for ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is ZFYVE28 (Zinc Finger FYVE-type containing 28) (LST2/2426), Biotin conjugate, 0.1mg/mL used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.