Ksp-Cadherin / CDH16 (Renal Cell Marker) (CDH16/2448), 1mg/mL

Catalog number BNUM2448-50

Price for BNUM2448-50

Size / count 1x 50 µL

About this product

This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUM2448-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Cadherin-16 (CDH16) ; Kidney-specific cadherin; Ksp-cadherin antibody
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CDH16
Gene ID: 1014
NCBI Gene ID: 513660
UniProt: O75309
Swiss Prot: O75309
Host: Mouse
Species Reactivity: Human
Reactivity: CDH16|Ksp-Cadherin
Immunogen: Recombinant fragment (around aa 371-507) of human CDH16 protein (exact sequence is proprietary)
Target Antigen: CDH16 | Ksp-Cadherin
Clonality: Monoclonal
Clone: CDH16/2448
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Normal kidney or renal cell carcinoma
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: 130 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse)
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Ksp-Cadherin / CDH16 (Renal Cell Marker) (CDH16/2448), 1mg/mL?

The catalog number for Ksp-Cadherin / CDH16 (Renal Cell Marker) (CDH16/2448), 1mg/mL is BNUM2448-50.

What sizes are available for Ksp-Cadherin / CDH16 (Renal Cell Marker) (CDH16/2448), 1mg/mL?

Ksp-Cadherin / CDH16 (Renal Cell Marker) (CDH16/2448), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Ksp-Cadherin / CDH16 (Renal Cell Marker) (CDH16/2448), 1mg/mL in stock?

Ksp-Cadherin / CDH16 (Renal Cell Marker) (CDH16/2448), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ksp-Cadherin / CDH16 (Renal Cell Marker) (CDH16/2448), 1mg/mL?

Ksp-Cadherin / CDH16 (Renal Cell Marker) (CDH16/2448), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Ksp-Cadherin / CDH16 (Renal Cell Marker) (CDH16/2448), 1mg/mL?

Estimated delivery time for Ksp-Cadherin / CDH16 (Renal Cell Marker) (CDH16/2448), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Ksp-Cadherin / CDH16 (Renal Cell Marker) (CDH16/2448), 1mg/mL?

The safety data sheet for Ksp-Cadherin / CDH16 (Renal Cell Marker) (CDH16/2448), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Ksp-Cadherin / CDH16 (Renal Cell Marker) (CDH16/2448), 1mg/mL used for?

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.