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Product details

HER-2 / c-erbB-2 / neu / CD340 (ERBB2/2452), 1mg/mL

Catalog number BNUM2452-50

Price for BNUM2452-50

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Size / count 1x 50 µL

About this product

This antibody recognizes a protein of 185 kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This MAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM2452-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
P185, CD340, Verb b2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ERBB2
Gene ID
2064
NCBI Gene ID
446352
UniProt
P04626
Swiss Prot
P04626
Host
Mouse
Species Reactivity
Human
Reactivity
C-ErbB-2|CD340|HER-2|Neu
Immunogen
Recombinant human HER-2 protein fragment (around aa 311-462) (exact sequence is proprietary)
Target Antigen
c-ErbB-2 | CD340 | HER-2 | Neu
Clonality
Monoclonal
Clone
ERBB2/2452
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IF (verified) |IHC, FFPE (verified)
Field of Research
Cancer, Signal transduction
Positive Control
SKBR-3 Cells or Breast Cancers.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
185 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for HER-2 / c-erbB-2 / neu / CD340 (ERBB2/2452), 1mg/mL?

The catalog number for HER-2 / c-erbB-2 / neu / CD340 (ERBB2/2452), 1mg/mL is BNUM2452-50.

What sizes are available for HER-2 / c-erbB-2 / neu / CD340 (ERBB2/2452), 1mg/mL?

HER-2 / c-erbB-2 / neu / CD340 (ERBB2/2452), 1mg/mL is available in the following size(s): 1x 50 µL.

Is HER-2 / c-erbB-2 / neu / CD340 (ERBB2/2452), 1mg/mL in stock?

HER-2 / c-erbB-2 / neu / CD340 (ERBB2/2452), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HER-2 / c-erbB-2 / neu / CD340 (ERBB2/2452), 1mg/mL?

HER-2 / c-erbB-2 / neu / CD340 (ERBB2/2452), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for HER-2 / c-erbB-2 / neu / CD340 (ERBB2/2452), 1mg/mL?

Estimated delivery time for HER-2 / c-erbB-2 / neu / CD340 (ERBB2/2452), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HER-2 / c-erbB-2 / neu / CD340 (ERBB2/2452), 1mg/mL?

The safety data sheet for HER-2 / c-erbB-2 / neu / CD340 (ERBB2/2452), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is HER-2 / c-erbB-2 / neu / CD340 (ERBB2/2452), 1mg/mL used for?

This antibody recognizes a protein of 185 kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This MAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of thi

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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