Flt3 / CD135 (FLT3/2458), CF647 conjugate, 0.1mg/mL

Catalog number BNC472458-500

Price for BNC472458-500

Size / count 1x 500 µL

About this product

Stem cell tyrosine kinase (STK-1) has been cloned from a CD34 hematopoietic stem cell enriched library and identified as the human homolog of a previously identified gene of Mouse origin designated either Flk-2 or Flt-3. The STK-1 cDNA encodes a protein of 993 amino acids with 85% identity to Flt-3/Flk-2. STK-1 is a member of the type III receptor tyrosine kinase family that includes Kit (steel factor receptor), Fms and PDGF. STK-1 expression in blood and marrow is restricted to CD34 cells, a population greatly enriched for hematopoietic stem/progenitor cells. STK-1 antiserum recognizes two polypeptides in these cells. The Mouse homolog of STK-1, designated Flt-3/Flk-2, is expressed at high levels in hematopoietic cells and also in neural, gonadal, hepatic and placental tissues. It has been suggested that STK-1 and its murine homolog Flt-3/Flk-2 may function as growth factor receptors on hematopoietic stem and/or progenitor cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472458-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD135; CD135 antigen; Fetal liver kinase 2; FL cytokine receptor; Flk2; FLT-3; Flt3; FLT3_HUMAN; FMS like tyrosine kinase 3; Fms related tyrosine kinase 3; Growth factor receptor tyrosine kinase type III; Ly-72; OTTHUMP0000004234; Receptor type tyrosine protein kinase FLT3; Stem cell tyrosine kinase 1; Stk 1; STK-1; Stk1; Tyrosine protein kinase receptor FLT3
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: FLT3
Gene ID: 2322
NCBI Gene ID: 507590
UniProt: P36888
Swiss Prot: P36888
Host: Mouse
Species Reactivity: Human
Reactivity: CD135|Flt3
Immunogen: Recombinant full-length human FLT3 protein
Target Antigen: CD135 | Flt3
Clonality: Monoclonal
Clone: FLT3/2458
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Human lymph node or MDAMB468 xenograft.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 160 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Flt3 / CD135 (FLT3/2458), CF647 conjugate, 0.1mg/mL?

The catalog number for Flt3 / CD135 (FLT3/2458), CF647 conjugate, 0.1mg/mL is BNC472458-500.

What sizes are available for Flt3 / CD135 (FLT3/2458), CF647 conjugate, 0.1mg/mL?

Flt3 / CD135 (FLT3/2458), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Flt3 / CD135 (FLT3/2458), CF647 conjugate, 0.1mg/mL in stock?

Flt3 / CD135 (FLT3/2458), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Flt3 / CD135 (FLT3/2458), CF647 conjugate, 0.1mg/mL?

Flt3 / CD135 (FLT3/2458), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Flt3 / CD135 (FLT3/2458), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Flt3 / CD135 (FLT3/2458), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Flt3 / CD135 (FLT3/2458), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Flt3 / CD135 (FLT3/2458), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029f061270361e1034e2/msds/bnc472458-500.pdf.

What is Flt3 / CD135 (FLT3/2458), CF647 conjugate, 0.1mg/mL used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.