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Product details

Flt3 / CD135 (FLT3/2458), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2458-500

Price for BNCB2458-500

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Size / count 1x 500 µL

About this product

Stem cell tyrosine kinase (STK-1) has been cloned from a CD34 hematopoietic stem cell enriched library and identified as the human homolog of a previously identified gene of Mouse origin designated either Flk-2 or Flt-3. The STK-1 cDNA encodes a protein of 993 amino acids with 85% identity to Flt-3/Flk-2. STK-1 is a member of the type III receptor tyrosine kinase family that includes Kit (steel factor receptor), Fms and PDGF. STK-1 expression in blood and marrow is restricted to CD34 cells, a population greatly enriched for hematopoietic stem/progenitor cells. STK-1 antiserum recognizes two polypeptides in these cells. The Mouse homolog of STK-1, designated Flt-3/Flk-2, is expressed at high levels in hematopoietic cells and also in neural, gonadal, hepatic and placental tissues. It has been suggested that STK-1 and its murine homolog Flt-3/Flk-2 may function as growth factor receptors on hematopoietic stem and/or progenitor cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB2458-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD135; CD135 antigen; Fetal liver kinase 2; FL cytokine receptor; Flk2; FLT-3; Flt3; FLT3_HUMAN; FMS like tyrosine kinase 3; Fms related tyrosine kinase 3; Growth factor receptor tyrosine kinase type III; Ly-72; OTTHUMP0000004234; Receptor type tyrosine protein kinase FLT3; Stem cell tyrosine kinase 1; Stk 1; STK-1; Stk1; Tyrosine protein kinase receptor FLT3
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
FLT3
Gene ID
2322
NCBI Gene ID
507590
UniProt
P36888
Swiss Prot
P36888
Host
Mouse
Species Reactivity
Human
Reactivity
CD135|Flt3
Immunogen
Recombinant full-length human FLT3 protein
Target Antigen
CD135 | Flt3
Clonality
Monoclonal
Clone
FLT3/2458
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Human lymph node or MDAMB468 xenograft.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
160 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Flt3 / CD135 (FLT3/2458), Biotin conjugate, 0.1mg/mL?

The catalog number for Flt3 / CD135 (FLT3/2458), Biotin conjugate, 0.1mg/mL is BNCB2458-500.

What sizes are available for Flt3 / CD135 (FLT3/2458), Biotin conjugate, 0.1mg/mL?

Flt3 / CD135 (FLT3/2458), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Flt3 / CD135 (FLT3/2458), Biotin conjugate, 0.1mg/mL in stock?

Flt3 / CD135 (FLT3/2458), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Flt3 / CD135 (FLT3/2458), Biotin conjugate, 0.1mg/mL?

Flt3 / CD135 (FLT3/2458), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Flt3 / CD135 (FLT3/2458), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Flt3 / CD135 (FLT3/2458), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Flt3 / CD135 (FLT3/2458), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Flt3 / CD135 (FLT3/2458), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Flt3 / CD135 (FLT3/2458), Biotin conjugate, 0.1mg/mL used for?

Stem cell tyrosine kinase (STK-1) has been cloned from a CD34 hematopoietic stem cell enriched library and identified as the human homolog of a previously identified gene of Mouse origin designated either Flk-2 or Flt-3. The STK-1 cDNA encodes a protein of 993 amino acids with 85% identity to Flt-3/

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

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