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Product details

Ki-67 (Proliferating Cell Marker) (MKI67/2461), CF640R conjugate, 0.1mg/mL

Catalog number BNC402461-100

Price for BNC402461-100

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Size / count 1x 100 µL

About this product

Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC402461-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
KI-67; Ki67; KI-67 Antigen (KIA) ; MKI67; Proliferation related Ki-67 antigen
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MKI67
Gene ID
4288
NCBI Gene ID
689823
UniProt
P46013
Swiss Prot
P46013
Host
Mouse
Species Reactivity
Human
Reactivity
Ki-67
Immunogen
Recombinant fragment of human Ki67 protein (around aa 2293-2478) (exact sequence is proprietary)
Target Antigen
Ki-67
Clonality
Monoclonal
Clone
MKI67/2461
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control
Any actively proliferating cells. Skin, Tonsil or Lymph Node
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
345 kDa and 395 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for Ki-67 (Proliferating Cell Marker) (MKI67/2461), CF640R conjugate, 0.1mg/mL?

The catalog number for Ki-67 (Proliferating Cell Marker) (MKI67/2461), CF640R conjugate, 0.1mg/mL is BNC402461-100.

What sizes are available for Ki-67 (Proliferating Cell Marker) (MKI67/2461), CF640R conjugate, 0.1mg/mL?

Ki-67 (Proliferating Cell Marker) (MKI67/2461), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Ki-67 (Proliferating Cell Marker) (MKI67/2461), CF640R conjugate, 0.1mg/mL in stock?

Ki-67 (Proliferating Cell Marker) (MKI67/2461), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ki-67 (Proliferating Cell Marker) (MKI67/2461), CF640R conjugate, 0.1mg/mL?

Ki-67 (Proliferating Cell Marker) (MKI67/2461), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Ki-67 (Proliferating Cell Marker) (MKI67/2461), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Ki-67 (Proliferating Cell Marker) (MKI67/2461), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Ki-67 (Proliferating Cell Marker) (MKI67/2461), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Ki-67 (Proliferating Cell Marker) (MKI67/2461), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Ki-67 (Proliferating Cell Marker) (MKI67/2461), CF640R conjugate, 0.1mg/mL used for?

Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

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