Ki-67 (Proliferating Cell Marker) (MKI67/2463), CF488A conjugate, 0.1mg/mL

Catalog number BNC882463-500

Price for BNC882463-500

Size / count 1x 500 µL

About this product

Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC882463-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: KI-67; Ki67; KI-67 Antigen (KIA) ; MKI67; Proliferation related Ki-67 antigen
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MKI67
Gene ID: 4288
NCBI Gene ID: 689823
UniProt: P46013
Swiss Prot: P46013
Host: Mouse
Species Reactivity: Human
Reactivity: Ki-67
Immunogen: Recombinant fragment of human Ki67 protein (around aa 2293-2478) (exact sequence is proprietary)
Target Antigen: Ki-67
Clonality: Monoclonal
Clone: MKI67/2463
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control: Any actively proliferating cells. Skin, Tonsil or Lymph Node
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 345 kDa and 395 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for Ki-67 (Proliferating Cell Marker) (MKI67/2463), CF488A conjugate, 0.1mg/mL?

The catalog number for Ki-67 (Proliferating Cell Marker) (MKI67/2463), CF488A conjugate, 0.1mg/mL is BNC882463-500.

What sizes are available for Ki-67 (Proliferating Cell Marker) (MKI67/2463), CF488A conjugate, 0.1mg/mL?

Ki-67 (Proliferating Cell Marker) (MKI67/2463), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Ki-67 (Proliferating Cell Marker) (MKI67/2463), CF488A conjugate, 0.1mg/mL in stock?

Ki-67 (Proliferating Cell Marker) (MKI67/2463), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ki-67 (Proliferating Cell Marker) (MKI67/2463), CF488A conjugate, 0.1mg/mL?

Ki-67 (Proliferating Cell Marker) (MKI67/2463), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Ki-67 (Proliferating Cell Marker) (MKI67/2463), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Ki-67 (Proliferating Cell Marker) (MKI67/2463), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Ki-67 (Proliferating Cell Marker) (MKI67/2463), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Ki-67 (Proliferating Cell Marker) (MKI67/2463), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Ki-67 (Proliferating Cell Marker) (MKI67/2463), CF488A conjugate, 0.1mg/mL used for?

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.