CD3e (T-Cell Marker) (UCHT1), 1mg/mL — image 1 of 4

Product details

CD3e (T-Cell Marker) (UCHT1), 1mg/mL

Catalog number BNUM2473-50

Price for BNUM2473-50

Size / count 1x 50 µL

About this product

Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR) . Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUM2473-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD3 epsilon; CD3 TCR complex; T cell antigen receptor complex epsilon subunit of T3; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E; TCRE; TiT3 complex
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD3E
Gene ID: 916
NCBI Gene ID: 3003
UniProt: P07766
Swiss Prot: P07766
Host: Mouse
Species Reactivity: Chimpanzee, Human
Reactivity: CD3e
Immunogen: Human infant thymocytes and peripheral blood lymphocytes from a Sezary Syndrome donor
Target Antigen: CD3e
Clonality: Monoclonal
Clone: UCHT1
Type: Primary
Source: Animal
Origin: Animal
Applications: Functional studies (published) |ELISA (published) |Flow, surface (verified) |IF (verified) |IP (published) |WB (published)
Positive Control: Human peripheral blood. Jurkat cells. Tonsil or lymph node.
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: 20 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. _x000D_ 1. Blood (1988) 71(3): 603-612. (immunofluorescence, western)_x000D_ 2. J Immunol Meth (1988) 106(1): 127-133. (ELISA)_x000D_ 3. J Exp Med (1991) 173: 7-17. (immunoprecipitation)_x000D_ 4. J Immunol (2002) 168: 3235-3241. (functional studies)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse)
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Frequently Asked Questions

What is the catalog number for CD3e (T-Cell Marker) (UCHT1), 1mg/mL?

The catalog number for CD3e (T-Cell Marker) (UCHT1), 1mg/mL is BNUM2473-50.

What sizes are available for CD3e (T-Cell Marker) (UCHT1), 1mg/mL?

CD3e (T-Cell Marker) (UCHT1), 1mg/mL is available in the following size(s): 1x 50 µL.

Is CD3e (T-Cell Marker) (UCHT1), 1mg/mL in stock?

CD3e (T-Cell Marker) (UCHT1), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD3e (T-Cell Marker) (UCHT1), 1mg/mL?

CD3e (T-Cell Marker) (UCHT1), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD3e (T-Cell Marker) (UCHT1), 1mg/mL?

Estimated delivery time for CD3e (T-Cell Marker) (UCHT1), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD3e (T-Cell Marker) (UCHT1), 1mg/mL?

The safety data sheet for CD3e (T-Cell Marker) (UCHT1), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD3e (T-Cell Marker) (UCHT1), 1mg/mL used for?

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.