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Product details

Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/2480), CF647 conjugate, 0.1mg/mL

Catalog number BNC472480-100

Price for BNC472480-100

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Size / count 1x 100 µL

About this product

Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e. g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC472480-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Coagulation Factor VIII; Factor VIII Related Antigen; F8VWF; von Willebrand Antigen 2; von Willebrand Disease (vWD)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
VWF
Gene ID
7450
NCBI Gene ID
440848
UniProt
P04275
Swiss Prot
P04275
Host
Mouse
Species Reactivity
Human
Reactivity
Factor VIII Related-Ag|von Willebrand Factor
Immunogen
Recombinant full-length human VWF protein
Target Antigen
Factor VIII Related-Ag | von Willebrand Factor
Clonality
Monoclonal
Clone
VWF/2480
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
HUVEC cells. Tonsil.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
250 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/2480), CF647 conjugate, 0.1mg/mL?

The catalog number for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/2480), CF647 conjugate, 0.1mg/mL is BNC472480-100.

What sizes are available for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/2480), CF647 conjugate, 0.1mg/mL?

Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/2480), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/2480), CF647 conjugate, 0.1mg/mL in stock?

Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/2480), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/2480), CF647 conjugate, 0.1mg/mL?

Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/2480), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/2480), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/2480), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/2480), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/2480), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a6061270361e105db6/msds/bnc472480-100.pdf.

What is Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/2480), CF647 conjugate, 0.1mg/mL used for?

Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and a

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

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