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Product details

RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9 (CPTC-EBAG9-2), CF647 conjugate, 0.1mg/mL

Catalog number BNC472502-500

Price for BNC472502-500

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Size / count 1x 500 µL

About this product

EBAG9, also known as RCAS1, is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers, including uterine, ovarian, and lung cancer cells, and acts as a ligand for a putative receptor present on peripheral lymphocytes. RCAS1 is highly expressed not only in cancer cells but also in non-tumor bile duct cells subject to immune attack. RCAS1 inhibits the in vitro growth of receptor-expressing cells and induces apoptosis, contributing to the ability of tumor cells to evade host immune surveillance. High expression of RCAS1 significantly correlates with tumor progression and with poor outcome for many cancer patients. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC472502-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
BAG9; cancer associated surface antigen; cancer associated surface antigen RCAS1; EB9; estrogen receptor binding fragment associated gene 9; PDAF; receptor binding cancer antigen expressed on SiSo cells
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
EBAG9
Gene ID
9166
NCBI Gene ID
409368
UniProt
O00559
Swiss Prot
O00559
Host
Mouse
Species Reactivity
Human
Reactivity
Estrogen Receptor Binding Site Associated, Antigen 9|RCAS1
Immunogen
Recombinant full-length human EBAG9 protein
Target Antigen
Estrogen Receptor Binding Site Associated, Antigen 9 | RCAS1
Clonality
Monoclonal
Clone
CPTC-EBAG9-2
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Positive Control
MCF-7, Jurkat; 293 cell lysates; Human skeletal muscle tissue.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
32 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9 (CPTC-EBAG9-2), CF647 conjugate, 0.1mg/mL?

The catalog number for RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9 (CPTC-EBAG9-2), CF647 conjugate, 0.1mg/mL is BNC472502-500.

What sizes are available for RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9 (CPTC-EBAG9-2), CF647 conjugate, 0.1mg/mL?

RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9 (CPTC-EBAG9-2), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9 (CPTC-EBAG9-2), CF647 conjugate, 0.1mg/mL in stock?

RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9 (CPTC-EBAG9-2), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9 (CPTC-EBAG9-2), CF647 conjugate, 0.1mg/mL?

RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9 (CPTC-EBAG9-2), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9 (CPTC-EBAG9-2), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9 (CPTC-EBAG9-2), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9 (CPTC-EBAG9-2), CF647 conjugate, 0.1mg/mL?

The safety data sheet for RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9 (CPTC-EBAG9-2), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e1029a3/msds/bnc472502-500.pdf.

What is RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9 (CPTC-EBAG9-2), CF647 conjugate, 0.1mg/mL used for?

EBAG9, also known as RCAS1, is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers, including uterine, ovarian, and lun

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

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