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Product details

NKX2.8 (NKX28/2547), 0.2mg/mL

Catalog number BNUB2547-100

Price for BNUB2547-100

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Size / count 1x 100 µL

About this product

The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB2547-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Homeobox protein NK 2 homolog H; Homeobox protein NK-2 homolog H; Homeobox protein Nkx 2.8; Homeobox protein Nkx-2.8; NK 2 homolog 8; NK 2 homolog H; NK2 homeobox 8; NK2 transcription factor related; locus 8; Nkx2 9; Nkx2-8; NKX2.8; NKX28_HUMAN; NKX2G; NKX2H; OTTHUMP00000027959
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NKX2-8
Gene ID
26257
NCBI Gene ID
234763
UniProt
O15522
Swiss Prot
O15522
Host
Mouse
Species Reactivity
Human
Reactivity
NKX2.8
Immunogen
Human recombinant NKX2.8 protein fragment (around aa 10-123) (exact sequence is proprietary)
Target Antigen
NKX2.8
Clonality
Monoclonal
Clone
NKX28/2547
Type
Primary
Source
Animal
Origin
Animal
Applications
WB (verified)
Positive Control
Human Liver, Kidney or Thyroid tissue (IHC).
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
26 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for NKX2.8 (NKX28/2547), 0.2mg/mL?

The catalog number for NKX2.8 (NKX28/2547), 0.2mg/mL is BNUB2547-100.

What sizes are available for NKX2.8 (NKX28/2547), 0.2mg/mL?

NKX2.8 (NKX28/2547), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is NKX2.8 (NKX28/2547), 0.2mg/mL in stock?

NKX2.8 (NKX28/2547), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NKX2.8 (NKX28/2547), 0.2mg/mL?

NKX2.8 (NKX28/2547), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for NKX2.8 (NKX28/2547), 0.2mg/mL?

Estimated delivery time for NKX2.8 (NKX28/2547), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NKX2.8 (NKX28/2547), 0.2mg/mL?

The safety data sheet for NKX2.8 (NKX28/2547), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is NKX2.8 (NKX28/2547), 0.2mg/mL used for?

The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patie

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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