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Product details

Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF594 conjugate, 0.1mg/mL

Catalog number BNC942573-500

Price for BNC942573-500

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Size / count 1x 500 µL

About this product

Focal adhesions are identified as areas within the plasma membrane of tissue culture cells that adhere tightly to the underlying substrate. In vivo, these regions are involved in the adhesion of cells to the extracellular matrix. Paxillin and vinculin are cytoskeletal, focal adhesion proteins that are components of a protein complex which links the Actin network to the plasma membrane. Vinculin binding sites have been identified on other cytoskeletal proteins, including talin and alpha-actinin each contain actin binding sites. Reportedly, vinculin is a potential plasma biomarker for Age-related Macular Degeneration (AMD) . The early detection of AMD using novel plasma biomarkers with genetic modeling may enable timely treatment and vision preservation in the elderly. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC942573-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CMD1W; CMH15; Epididymis luminal protein 114; HEL114; Metavinculin; MV; MVCL; VCL; VINC
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
VCL
Gene ID
7414
NCBI Gene ID
643896
UniProt
P18206
Swiss Prot
P18206
Host
Mouse
Species Reactivity
Human, Mouse
Reactivity
Vinculin
Immunogen
Recombinant fragment (around aa 174-322) of human Vinculin (VCL) protein (exact sequence is proprietary)
Target Antigen
Vinculin
Clonality
Monoclonal
Clone
VCL/2573
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Human Bladder and Testis.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
117 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF594 conjugate, 0.1mg/mL?

The catalog number for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF594 conjugate, 0.1mg/mL is BNC942573-500.

What sizes are available for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF594 conjugate, 0.1mg/mL?

Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF594 conjugate, 0.1mg/mL in stock?

Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF594 conjugate, 0.1mg/mL?

Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF594 conjugate, 0.1mg/mL used for?

Focal adhesions are identified as areas within the plasma membrane of tissue culture cells that adhere tightly to the underlying substrate. In vivo, these regions are involved in the adhesion of cells to the extracellular matrix. Paxillin and vinculin are cytoskeletal, focal adhesion proteins that a

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

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