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Product details
Catalog number BNUM2573-50
Price for BNUM2573-50
Size / count 1x 50 µL
Focal adhesions are identified as areas within the plasma membrane of tissue culture cells that adhere tightly to the underlying substrate. In vivo, these regions are involved in the adhesion of cells to the extracellular matrix. Paxillin and vinculin are cytoskeletal, focal adhesion proteins that are components of a protein complex which links the Actin network to the plasma membrane. Vinculin binding sites have been identified on other cytoskeletal proteins, including talin and alpha-actinin each contain actin binding sites. Reportedly, vinculin is a potential plasma biomarker for Age-related Macular Degeneration (AMD) . The early detection of AMD using novel plasma biomarkers with genetic modeling may enable timely treatment and vision preservation in the elderly. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), 1mg/mL is BNUM2573-50.
Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), 1mg/mL is available in the following size(s): 1x 50 µL.
Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), 1mg/mL is manufactured by Biotium.
Estimated delivery time for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), 1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
Focal adhesions are identified as areas within the plasma membrane of tissue culture cells that adhere tightly to the underlying substrate. In vivo, these regions are involved in the adhesion of cells to the extracellular matrix. Paxillin and vinculin are cytoskeletal, focal adhesion proteins that a
Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.
Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.
Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.
