Vinculin (Marker of Age-related Macular Degeneration) (VCL/2575), CF488A conjugate, 0.1mg/mL

Catalog number BNC882575-500

Price for BNC882575-500

Size / count 1x 500 µL

About this product

Focal adhesions are identified as areas within the plasma membrane of tissue culture cells that adhere tightly to the underlying substrate. In vivo, these regions are involved in the adhesion of cells to the extracellular matrix. Paxillin and vinculin are cytoskeletal, focal adhesion proteins that are components of a protein complex which links the Actin network to the plasma membrane. Vinculin binding sites have been identified on other cytoskeletal proteins, including talin and alpha-actinin each contain actin binding sites. Reportedly, vinculin is a potential plasma biomarker for Age-related Macular Degeneration (AMD) . The early detection of AMD using novel plasma biomarkers with genetic modeling may enable timely treatment and vision preservation in the elderly. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC882575-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CMD1W; CMH15; Epididymis luminal protein 114; HEL114; Metavinculin; MV; MVCL; VCL; VINC
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: VCL
Gene ID: 7414
NCBI Gene ID: 643896
UniProt: P18206
Swiss Prot: P18206
Host: Mouse
Species Reactivity: Human
Reactivity: Vinculin
Immunogen: Recombinant fragment (around aa 174-322) of human Vinculin (VCL) protein (exact sequence is proprietary)
Target Antigen: Vinculin
Clonality: Monoclonal
Clone: VCL/2575
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Positive Control: A431, K562, NIH3T3, U-87, THP-1 cells. Human Bladder and Testis.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 117 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2575), CF488A conjugate, 0.1mg/mL?

The catalog number for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2575), CF488A conjugate, 0.1mg/mL is BNC882575-500.

What sizes are available for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2575), CF488A conjugate, 0.1mg/mL?

Vinculin (Marker of Age-related Macular Degeneration) (VCL/2575), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Vinculin (Marker of Age-related Macular Degeneration) (VCL/2575), CF488A conjugate, 0.1mg/mL in stock?

Vinculin (Marker of Age-related Macular Degeneration) (VCL/2575), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Vinculin (Marker of Age-related Macular Degeneration) (VCL/2575), CF488A conjugate, 0.1mg/mL?

Vinculin (Marker of Age-related Macular Degeneration) (VCL/2575), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2575), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2575), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2575), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2575), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Vinculin (Marker of Age-related Macular Degeneration) (VCL/2575), CF488A conjugate, 0.1mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.