NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), CF405S conjugate, 0.1mg/mL

Catalog number BNC042576-100

Price for BNC042576-100

Size / count 1x 100 µL

About this product

NKX3. 1 is a prostate specific gene encoding a transcription factor that plays an important role in normal prostate development and carcinogenesis. It is a prostatic tumor suppressor gene located on chromosome 8p21. 2, which frequently undergoes a loss of heterozygosity. NKX3. 1 expression is highly restricted in prostate epithelial cells and therefore can be used as a diagnostic biomarker for prostate cancer and other metastatic lesions of prostatic origin. Furthermore, NKX3. 1 shows better sensitivity than Prostate Specific Antigen (PSA) for identifying metastatic prostatic adenocarcinoma. This suggests that immunohistochemical staining of NKX3. 1, along with other prostate-restricted markers, may be valuable for the definitive determination of prostatic origin in poorly differentiated metastatic carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC042576-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: NK3 Homeobox 1; Homeobox Protein NK-3 Homolog A; NKX3-1; NKX3A; NK3 Transcription Factor Related; Locus 1 (Drosophila) ; NK3 Transcription Factor Related; Locus 1; NK Homeobox (Drosophila) ; Family 3; A; NK3 Transcription Factor Homolog A; NK Homeobox; Family 3; A; Homeobox Protein Nkx-3.1; BAPX2; NKX3
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: NKX3-1
Gene ID: 4824
NCBI Gene ID: 55999
UniProt: Q99801
Swiss Prot: Q99801
Host: Mouse
Species Reactivity: Human
Reactivity: NKX3.1
Immunogen: Recombinant fragment (around aa 92-224) of human NKX3.1 protein (exact sequence is proprietary)
Target Antigen: NKX3.1
Clonality: Monoclonal
Clone: NKX3.1/2576
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Highly expressed in the prostate and at a lower level in the testis.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 35 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2c, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), CF405S conjugate, 0.1mg/mL?

The catalog number for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), CF405S conjugate, 0.1mg/mL is BNC042576-100.

What sizes are available for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), CF405S conjugate, 0.1mg/mL?

NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), CF405S conjugate, 0.1mg/mL in stock?

NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), CF405S conjugate, 0.1mg/mL?

NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), CF405S conjugate, 0.1mg/mL?

The safety data sheet for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0299061270361e1013f7/msds/bnc042576-100.pdf.

What is NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), CF405S conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.