NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), 1mg/mL

Catalog number BNUM2576-50

Price for BNUM2576-50

Size / count 1x 50 µL

About this product

NKX3. 1 is a prostate specific gene encoding a transcription factor that plays an important role in normal prostate development and carcinogenesis. It is a prostatic tumor suppressor gene located on chromosome 8p21. 2, which frequently undergoes a loss of heterozygosity. NKX3. 1 expression is highly restricted in prostate epithelial cells and therefore can be used as a diagnostic biomarker for prostate cancer and other metastatic lesions of prostatic origin. Furthermore, NKX3. 1 shows better sensitivity than Prostate Specific Antigen (PSA) for identifying metastatic prostatic adenocarcinoma. This suggests that immunohistochemical staining of NKX3. 1, along with other prostate-restricted markers, may be valuable for the definitive determination of prostatic origin in poorly differentiated metastatic carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUM2576-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: NK3 Homeobox 1; Homeobox Protein NK-3 Homolog A; NKX3-1; NKX3A; NK3 Transcription Factor Related; Locus 1 (Drosophila) ; NK3 Transcription Factor Related; Locus 1; NK Homeobox (Drosophila) ; Family 3; A; NK3 Transcription Factor Homolog A; NK Homeobox; Family 3; A; Homeobox Protein Nkx-3.1; BAPX2; NKX3
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: NKX3-1
Gene ID: 4824
NCBI Gene ID: 55999
UniProt: Q99801
Swiss Prot: Q99801
Host: Mouse
Species Reactivity: Human
Reactivity: NKX3.1
Immunogen: Recombinant fragment (around aa 92-224) of human NKX3.1 protein (exact sequence is proprietary)
Target Antigen: NKX3.1
Clonality: Monoclonal
Clone: NKX3.1/2576
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Highly expressed in the prostate and at a lower level in the testis.
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: 35 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2c, kappa
Species: Mus musculus (mouse)
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Frequently Asked Questions

What is the catalog number for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), 1mg/mL?

The catalog number for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), 1mg/mL is BNUM2576-50.

What sizes are available for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), 1mg/mL?

NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), 1mg/mL is available in the following size(s): 1x 50 µL.

Is NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), 1mg/mL in stock?

NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), 1mg/mL?

NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), 1mg/mL?

Estimated delivery time for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), 1mg/mL?

The safety data sheet for NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0296061270361e1000bc/msds/bnum2576-50.pdf.

What is NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/2576), 1mg/mL used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.