Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), CF647 conjugate, 0.1mg/mL

Catalog number BNC472587-500

Price for BNC472587-500

Size / count 1x 500 µL

About this product

Cyclin E belongs to the highly conserved cyclin family, whose members exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. Cyclin E accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Cyclin E overexpression has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472587-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CCNE1; Cyclin E1; G1/S-specific cyclin-E1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CCNE1
Gene ID: 898
NCBI Gene ID: 244723
UniProt: P24864
Swiss Prot: P24864
Host: Mouse
Species Reactivity: Human
Reactivity: Cyclin E
Immunogen: Recombinant human Cyclin E (CCNE1) protein fragment (around aa 10-176) (exact sequence is proprietary)
Target Antigen: Cyclin E
Clonality: Monoclonal
Clone: CCNE1/2587
Type: Primary
Source: Animal
Origin: Animal
Positive Control: HeLa Cells. Breast or Colon Carcinoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 53 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), CF647 conjugate, 0.1mg/mL?

The catalog number for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), CF647 conjugate, 0.1mg/mL is BNC472587-500.

What sizes are available for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), CF647 conjugate, 0.1mg/mL?

Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), CF647 conjugate, 0.1mg/mL in stock?

Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), CF647 conjugate, 0.1mg/mL?

Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a0061270361e10386e/msds/bnc472587-500.pdf.

What is Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), CF647 conjugate, 0.1mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.