Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2587-500

Price for BNCB2587-500

Size / count 1x 500 µL

About this product

Cyclin E belongs to the highly conserved cyclin family, whose members exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. Cyclin E accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Cyclin E overexpression has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB2587-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CCNE1; Cyclin E1; G1/S-specific cyclin-E1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CCNE1
Gene ID: 898
NCBI Gene ID: 244723
UniProt: P24864
Swiss Prot: P24864
Host: Mouse
Species Reactivity: Human
Reactivity: Cyclin E
Immunogen: Recombinant human Cyclin E (CCNE1) protein fragment (around aa 10-176) (exact sequence is proprietary)
Target Antigen: Cyclin E
Clonality: Monoclonal
Clone: CCNE1/2587
Type: Primary
Source: Animal
Origin: Animal
Positive Control: HeLa Cells. Breast or Colon Carcinoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 53 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), Biotin conjugate, 0.1mg/mL?

The catalog number for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), Biotin conjugate, 0.1mg/mL is BNCB2587-500.

What sizes are available for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), Biotin conjugate, 0.1mg/mL?

Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), Biotin conjugate, 0.1mg/mL in stock?

Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), Biotin conjugate, 0.1mg/mL?

Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cyclin E (G1/S-Phase Cyclin) (CCNE1/2587), Biotin conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.