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Product details
Catalog number BNC042622-100
Price for BNC042622-100
Size / count 1x 100 µL
Mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) . Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were found at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45% of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability has been interpreted to suggest that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF405S conjugate, 0.1mg/mL is BNC042622-100.
MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
Mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) . Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were found at high frequency in HNPCC and were shown to be associated w
Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.
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