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Product details

MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL

Catalog number BNC882622-100

Price for BNC882622-100

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Size / count 1x 100 µL

About this product

Mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) . Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were found at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45% of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability has been interpreted to suggest that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC882622-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
BAT26; COCA1; DNA mismatch repair protein Msh2; FCC1; hMSH2; HNPCC1; LCFS2; MSH2; MutS homolog 2; MutS homolog 2 colon cancer nonpolyposis type 1; MutS protein homolog 2
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MSH2
Gene ID
4436
NCBI Gene ID
597656
UniProt
IDP43246
Swiss Prot
IDP43246
Host
Mouse
Species Reactivity
Human
Reactivity
MSH2
Immunogen
Recombinant fragment (around aa 327-427) of human MSH2 protein (exact sequence is proprietary)
Target Antigen
MSH2
Clonality
Monoclonal
Clone
MSH2/2622
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control
A549 or HepG2 cells. Colon, Thyroid, Testis or Lymph Node.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
100 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL?

The catalog number for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL is BNC882622-100.

What sizes are available for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL?

MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL in stock?

MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL?

MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL?

The safety data sheet for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL used for?

Mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) . Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were found at high frequency in HNPCC and were shown to be associated w

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

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