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Product details
Catalog number BNC882622-500
Price for BNC882622-500
Size / count 1x 500 µL
Mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) . Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were found at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45% of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability has been interpreted to suggest that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL is BNC882622-500.
MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
Mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) . Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were found at high frequency in HNPCC and were shown to be associated w
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Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.
