• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF594 conjugate, 0.1mg/mL

Catalog number BNC942622-500

Price for BNC942622-500

Sign In for Pricing

Size / count 1x 500 µL

About this product

Mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) . Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were found at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45% of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability has been interpreted to suggest that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC942622-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
BAT26; COCA1; DNA mismatch repair protein Msh2; FCC1; hMSH2; HNPCC1; LCFS2; MSH2; MutS homolog 2; MutS homolog 2 colon cancer nonpolyposis type 1; MutS protein homolog 2
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MSH2
Gene ID
4436
NCBI Gene ID
597656
UniProt
IDP43246
Swiss Prot
IDP43246
Host
Mouse
Species Reactivity
Human
Reactivity
MSH2
Immunogen
Recombinant fragment (around aa 327-427) of human MSH2 protein (exact sequence is proprietary)
Target Antigen
MSH2
Clonality
Monoclonal
Clone
MSH2/2622
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control
A549 or HepG2 cells. Colon, Thyroid, Testis or Lymph Node.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
100 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF594 conjugate, 0.1mg/mL?

The catalog number for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF594 conjugate, 0.1mg/mL is BNC942622-500.

What sizes are available for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF594 conjugate, 0.1mg/mL?

MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF594 conjugate, 0.1mg/mL in stock?

MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF594 conjugate, 0.1mg/mL?

MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF594 conjugate, 0.1mg/mL?

The safety data sheet for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF594 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102a11/msds/bnc942622-500.pdf.

What is MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), CF594 conjugate, 0.1mg/mL used for?

Mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) . Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were found at high frequency in HNPCC and were shown to be associated w

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

You Might Also Like
CD4 (EDU-2), CF405S conjugate, 0.1mg/mL
CD4 (EDU-2), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040345-100
CD3e (CRIS-7), CF640R conjugate, 0.1mg/mL
CD3e (CRIS-7), CF640R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC401050-500
CD63 (MX-49.129.5), CF405S conjugate, 0.1mg/mL
CD63 (MX-49.129.5), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040525-500
CD54 / ICAM-1 (15.2), CF568 conjugate, 0.1mg/mL
CD54 / ICAM-1 (15.2), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC682853-500
HLA-Aw32 & HLA-A25 (MHC I) (CATA-1), CF647 conjugate, 0.1mg/mL
HLA-Aw32 & HLA-A25 (MHC I) (CATA-1), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC471073-100
TGF-beta (1D11.16.8), CF568 conjugate, 0.1mg/mL
TGF-beta (1D11.16.8), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680977-100
CD3e (B-B12), CF647 conjugate, 0.1mg/mL
CD3e (B-B12), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC471052-500
CD106 / VCAM1 (B-K9), CF594 conjugate, 0.1mg/mL
CD106 / VCAM1 (B-K9), CF594 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC940304-100