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Product details
Catalog number BNUB2622-100
Price for BNUB2622-100
Size / count 1x 100 µL
Mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) . Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were found at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45% of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability has been interpreted to suggest that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL is BNUB2622-100.
MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL is available in the following size(s): 1x 100 µL.
MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL is manufactured by Biotium.
Estimated delivery time for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029c061270361e102431/msds/bnub2622-100.pdf.
Mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) . Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were found at high frequency in HNPCC and were shown to be associated w
Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.
A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.
Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.
