MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL

Catalog number BNUB2622-500

Price for BNUB2622-500

Size / count 1x 500 µL

About this product

Mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) . Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were found at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45% of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability has been interpreted to suggest that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB2622-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BAT26; COCA1; DNA mismatch repair protein Msh2; FCC1; hMSH2; HNPCC1; LCFS2; MSH2; MutS homolog 2; MutS homolog 2 colon cancer nonpolyposis type 1; MutS protein homolog 2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MSH2
Gene ID: 4436
NCBI Gene ID: 597656
UniProt: IDP43246
Swiss Prot: IDP43246
Host: Mouse
Species Reactivity: Human
Reactivity: MSH2
Immunogen: Recombinant fragment (around aa 327-427) of human MSH2 protein (exact sequence is proprietary)
Target Antigen: MSH2
Clonality: Monoclonal
Clone: MSH2/2622
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control: A549 or HepG2 cells. Colon, Thyroid, Testis or Lymph Node.
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 100 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL?

The catalog number for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL is BNUB2622-500.

What sizes are available for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL?

MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL in stock?

MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL?

MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL?

Estimated delivery time for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL?

The safety data sheet for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 0.2mg/mL used for?

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.