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Product details
Catalog number BNUM2622-50
Price for BNUM2622-50
Size / count 1x 50 µL
Mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) . Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were found at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45% of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability has been interpreted to suggest that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 1mg/mL is BNUM2622-50.
MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 1mg/mL is available in the following size(s): 1x 50 µL.
MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 1mg/mL is manufactured by Biotium.
Estimated delivery time for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for MSH2 (DNA Mismatch Repair Marker) (MSH2/2622), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
Mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) . Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were found at high frequency in HNPCC and were shown to be associated w
Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.
Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.
Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.
