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Product details

MTF1 (MTF1/2649), CF405S conjugate, 0.1mg/mL

Catalog number BNC042649-500

Price for BNC042649-500

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Size / count 1x 500 µL

About this product

The metal-responsive element (MRE) -binding transcription factor (MTF-1) stimulates the expression of metallothioneins in response to the exposure of cells to heavy metals. MTF-1 contains six zinc fingers in the DNA binding domain. The phosphorylation of MTF-1 in response to metal exposure appears to play a significant role in the ability of MTF-1 to activate metallothionein transcription. In addition to its role in metallothionein activation, MTF-1 is involved in a post-transcription regulatory complex for ribosomal protein S25. MTF-1, La and p53 inhibit the nuclear export of S25 mRNA in response to nutrient depravation. Furthermore, MTF-1 acts as a chromatin insulator on integrated transgenes in cultured cells to insulate active loci against chromatin silencing. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC042649-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Metal regulatory transcription factor 1; Metal response element binding transcription factor 1; Metal responsive transcription factor 1; MRE-binding transcription factor 1; MTF1; Transcription factor MTF1; Zinc regulatory factor (ZRF)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MTF1
Gene ID
4520
NCBI Gene ID
471991
UniProt
Q14872
Swiss Prot
Q14872
Host
Mouse
Species Reactivity
Human
Reactivity
MTF1
Immunogen
Recombinant full-length human MTF1 protein
Target Antigen
MTF1
Clonality
Monoclonal
Clone
MTF1/2649
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Human kidney.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
70 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S

Frequently Asked Questions

What is the catalog number for MTF1 (MTF1/2649), CF405S conjugate, 0.1mg/mL?

The catalog number for MTF1 (MTF1/2649), CF405S conjugate, 0.1mg/mL is BNC042649-500.

What sizes are available for MTF1 (MTF1/2649), CF405S conjugate, 0.1mg/mL?

MTF1 (MTF1/2649), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MTF1 (MTF1/2649), CF405S conjugate, 0.1mg/mL in stock?

MTF1 (MTF1/2649), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MTF1 (MTF1/2649), CF405S conjugate, 0.1mg/mL?

MTF1 (MTF1/2649), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MTF1 (MTF1/2649), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for MTF1 (MTF1/2649), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MTF1 (MTF1/2649), CF405S conjugate, 0.1mg/mL?

The safety data sheet for MTF1 (MTF1/2649), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MTF1 (MTF1/2649), CF405S conjugate, 0.1mg/mL used for?

The metal-responsive element (MRE) -binding transcription factor (MTF-1) stimulates the expression of metallothioneins in response to the exposure of cells to heavy metals. MTF-1 contains six zinc fingers in the DNA binding domain. The phosphorylation of MTF-1 in response to metal exposure appears t

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

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