MTF1 (MTF1/2649), CF647 conjugate, 0.1mg/mL

Catalog number BNC472649-500

Price for BNC472649-500

Size / count 1x 500 µL

About this product

The metal-responsive element (MRE) -binding transcription factor (MTF-1) stimulates the expression of metallothioneins in response to the exposure of cells to heavy metals. MTF-1 contains six zinc fingers in the DNA binding domain. The phosphorylation of MTF-1 in response to metal exposure appears to play a significant role in the ability of MTF-1 to activate metallothionein transcription. In addition to its role in metallothionein activation, MTF-1 is involved in a post-transcription regulatory complex for ribosomal protein S25. MTF-1, La and p53 inhibit the nuclear export of S25 mRNA in response to nutrient depravation. Furthermore, MTF-1 acts as a chromatin insulator on integrated transgenes in cultured cells to insulate active loci against chromatin silencing. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472649-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Metal regulatory transcription factor 1; Metal response element binding transcription factor 1; Metal responsive transcription factor 1; MRE-binding transcription factor 1; MTF1; Transcription factor MTF1; Zinc regulatory factor (ZRF)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MTF1
Gene ID: 4520
NCBI Gene ID: 471991
UniProt: Q14872
Swiss Prot: Q14872
Host: Mouse
Species Reactivity: Human
Reactivity: MTF1
Immunogen: Recombinant full-length human MTF1 protein
Target Antigen: MTF1
Clonality: Monoclonal
Clone: MTF1/2649
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Human kidney.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 70 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for MTF1 (MTF1/2649), CF647 conjugate, 0.1mg/mL?

The catalog number for MTF1 (MTF1/2649), CF647 conjugate, 0.1mg/mL is BNC472649-500.

What sizes are available for MTF1 (MTF1/2649), CF647 conjugate, 0.1mg/mL?

MTF1 (MTF1/2649), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MTF1 (MTF1/2649), CF647 conjugate, 0.1mg/mL in stock?

MTF1 (MTF1/2649), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MTF1 (MTF1/2649), CF647 conjugate, 0.1mg/mL?

MTF1 (MTF1/2649), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MTF1 (MTF1/2649), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for MTF1 (MTF1/2649), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MTF1 (MTF1/2649), CF647 conjugate, 0.1mg/mL?

The safety data sheet for MTF1 (MTF1/2649), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029c061270361e10215f/msds/bnc472649-500.pdf.

What is MTF1 (MTF1/2649), CF647 conjugate, 0.1mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.