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Product details

CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF488A conjugate, 0.1mg/mL

Catalog number BNC882673-100

Price for BNC882673-100

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Size / count 1x 100 µL

About this product

CD117, also known as c-kit, is a member if the immunoglobin superfamily. It is a receptor tyrosine kinase that is expressed on hematopoietic progenitor cells. It binds to the c-kit ligand KITLG/SCF and has roles in cell survival and cell proliferation. Upon ligand binding, it activates a number of signaling pathways. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC882673-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD117; c-Kit; p145; Mast/stem Cell Growth Factor Receptor
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KIT
Gene ID
3815
NCBI Gene ID
479754
UniProt
P10721
Swiss Prot
P10721
Host
Mouse
Species Reactivity
Human
Reactivity
C-Kit|CD117
Immunogen
Recombinant full-length human KIT protein
Target Antigen
c-Kit | CD117
Clonality
Monoclonal
Clone
KIT/2673
Type
Primary
Source
Animal
Origin
Animal
Field of Research
Cancer, Signal transduction
Positive Control
Gastrointestinal Stromal Tumor (GIST) or testicular germ cell tumor. Melanocytes in the basal layer of the epidermis and mast cells in the dermis of normal skin.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
145 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF488A conjugate, 0.1mg/mL?

The catalog number for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF488A conjugate, 0.1mg/mL is BNC882673-100.

What sizes are available for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF488A conjugate, 0.1mg/mL?

CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF488A conjugate, 0.1mg/mL in stock?

CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF488A conjugate, 0.1mg/mL?

CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF488A conjugate, 0.1mg/mL?

The safety data sheet for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF488A conjugate, 0.1mg/mL used for?

CD117, also known as c-kit, is a member if the immunoglobin superfamily. It is a receptor tyrosine kinase that is expressed on hematopoietic progenitor cells. It binds to the c-kit ligand KITLG/SCF and has roles in cell survival and cell proliferation. Upon ligand binding, it activates a number of s

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

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