CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2674), CF640R conjugate, 0.1mg/mL

Catalog number BNC402674-500

Price for BNC402674-500

Size / count 1x 500 µL

About this product

CD117, also known as c-kit, is a member if the immunoglobin superfamily. It is a receptor tyrosine kinase that is expressed on hematopoietic progenitor cells. It binds to the c-kit ligand KITLG/SCF and has roles in cell survival and cell proliferation. Upon ligand binding, it activates a number of signaling pathways. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC402674-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD117; c-Kit; p145; Mast/stem Cell Growth Factor Receptor
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: KIT
Gene ID: 3815
NCBI Gene ID: 479754
UniProt: P10721
Swiss Prot: P10721
Host: Mouse
Species Reactivity: Human
Reactivity: C-Kit|CD117
Immunogen: Recombinant full-length human KIT protein
Target Antigen: c-Kit | CD117
Clonality: Monoclonal
Clone: KIT/2674
Type: Primary
Source: Animal
Origin: Animal
Field of Research: Cancer, Signal transduction
Positive Control: Gastrointestinal Stromal Tumor (GIST) or testicular germ cell tumor. Melanocytes in the basal layer of the epidermis and mast cells in the dermis of normal skin.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 145 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2c, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2674), CF640R conjugate, 0.1mg/mL?

The catalog number for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2674), CF640R conjugate, 0.1mg/mL is BNC402674-500.

What sizes are available for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2674), CF640R conjugate, 0.1mg/mL?

CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2674), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2674), CF640R conjugate, 0.1mg/mL in stock?

CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2674), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2674), CF640R conjugate, 0.1mg/mL?

CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2674), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2674), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2674), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2674), CF640R conjugate, 0.1mg/mL?

The safety data sheet for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2674), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2674), CF640R conjugate, 0.1mg/mL used for?

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.