PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF405S conjugate, 0.1mg/mL

Catalog number BNC042676-500

Price for BNC042676-500

Size / count 1x 500 µL

About this product

Recognizes a protein of about 31 kDa, which is identified as PD-L2 (same as PDCD1LG2) . Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator) . The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC042676-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: B7 dendritic cell molecule; B7-DC; B7DC; Btdc; Butyrophilin B7DC; CD273; PD-L2; PDCD1L2; PDCD1LG2; PDL2; Programmed death ligand 2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: PDCD1LG2
Gene ID: 80380
NCBI Gene ID: 532279; 617872
UniProt: Q9Q51
Swiss Prot: Q9Q51
Host: Mouse
Species Reactivity: Human
Reactivity: CD273|PD-L2|PDCD1LG2
Immunogen: Recombinant fragment (around aa 27-220) of human PD-L2 protein (exact sequence is proprietary)
Target Antigen: CD273 | PD-L2 | PDCD1LG2
Clonality: Monoclonal
Clone: PDL2/2676
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow (verified) |IF (verified) |WB (verified)
Positive Control: Jurakt, HepG2, THP-1, RAW, NIH3T3, U87 cells Placenta or Pancreas. Thyroid Carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 31 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF405S conjugate, 0.1mg/mL?

The catalog number for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF405S conjugate, 0.1mg/mL is BNC042676-500.

What sizes are available for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF405S conjugate, 0.1mg/mL?

PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF405S conjugate, 0.1mg/mL in stock?

PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF405S conjugate, 0.1mg/mL?

PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF405S conjugate, 0.1mg/mL?

The safety data sheet for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF405S conjugate, 0.1mg/mL used for?

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.