PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF640R conjugate, 0.1mg/mL

Catalog number BNC402676-100

Price for BNC402676-100

Size / count 1x 100 µL

About this product

Recognizes a protein of about 31 kDa, which is identified as PD-L2 (same as PDCD1LG2) . Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator) . The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC402676-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: B7 dendritic cell molecule; B7-DC; B7DC; Btdc; Butyrophilin B7DC; CD273; PD-L2; PDCD1L2; PDCD1LG2; PDL2; Programmed death ligand 2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: PDCD1LG2
Gene ID: 80380
NCBI Gene ID: 532279; 617872
UniProt: Q9Q51
Swiss Prot: Q9Q51
Host: Mouse
Species Reactivity: Human
Reactivity: CD273|PD-L2|PDCD1LG2
Immunogen: Recombinant fragment (around aa 27-220) of human PD-L2 protein (exact sequence is proprietary)
Target Antigen: CD273 | PD-L2 | PDCD1LG2
Clonality: Monoclonal
Clone: PDL2/2676
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow (verified) |IF (verified) |WB (verified)
Positive Control: Jurakt, HepG2, THP-1, RAW, NIH3T3, U87 cells Placenta or Pancreas. Thyroid Carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 31 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF640R conjugate, 0.1mg/mL?

The catalog number for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF640R conjugate, 0.1mg/mL is BNC402676-100.

What sizes are available for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF640R conjugate, 0.1mg/mL?

PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF640R conjugate, 0.1mg/mL in stock?

PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF640R conjugate, 0.1mg/mL?

PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF640R conjugate, 0.1mg/mL?

The safety data sheet for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF640R conjugate, 0.1mg/mL used for?

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.