PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF647 conjugate, 0.1mg/mL

Catalog number BNC472676-100

Price for BNC472676-100

Size / count 1x 100 µL

About this product

Recognizes a protein of about 31 kDa, which is identified as PD-L2 (same as PDCD1LG2) . Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator) . The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472676-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: B7 dendritic cell molecule; B7-DC; B7DC; Btdc; Butyrophilin B7DC; CD273; PD-L2; PDCD1L2; PDCD1LG2; PDL2; Programmed death ligand 2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: PDCD1LG2
Gene ID: 80380
NCBI Gene ID: 532279; 617872
UniProt: Q9Q51
Swiss Prot: Q9Q51
Host: Mouse
Species Reactivity: Human
Reactivity: CD273|PD-L2|PDCD1LG2
Immunogen: Recombinant fragment (around aa 27-220) of human PD-L2 protein (exact sequence is proprietary)
Target Antigen: CD273 | PD-L2 | PDCD1LG2
Clonality: Monoclonal
Clone: PDL2/2676
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow (verified) |IF (verified) |WB (verified)
Positive Control: Jurakt, HepG2, THP-1, RAW, NIH3T3, U87 cells Placenta or Pancreas. Thyroid Carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 31 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF647 conjugate, 0.1mg/mL?

The catalog number for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF647 conjugate, 0.1mg/mL is BNC472676-100.

What sizes are available for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF647 conjugate, 0.1mg/mL?

PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF647 conjugate, 0.1mg/mL in stock?

PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF647 conjugate, 0.1mg/mL?

PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF647 conjugate, 0.1mg/mL?

The safety data sheet for PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e100a1f/msds/bnc472676-100.pdf.

What is PD-L2 / PDCD1LG2 / CD273 (PDL2/2676), CF647 conjugate, 0.1mg/mL used for?

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.