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Product details

ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2683), CF568 conjugate, 0.1mg/mL

Catalog number BNC682683-500

Price for BNC682683-500

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Size / count 1x 500 µL

About this product

Recognizes a protein of 110 kDa, identified as Excision Repair Cross Complementing 1 (ERCC1) . It is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae, which is required in mitotic intrachromosomal recombination and repair. ERCC1 is required in repair of cisplatin-induced DNA adducts and ultraviolet (UV) -induced DNA damage. High expression of ERCC1 has been linked to tumor progression in a variety of cancers including non-small cell lung cancer (NSCLC), squamous cell carcinoma of the head, ovarian cancer and esophageal cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC682683-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
COFS4; DNA excision repair protein ERCC1; ERCC1; Excision repair cross complementing 1; RAD10; UV20
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ERCC1
Gene ID
2067
NCBI Gene ID
435981
UniProt
P07992
Swiss Prot
P07992
Host
Mouse
Species Reactivity
Human
Reactivity
ERCC1|RAD10
Immunogen
Recombinant fragment (around aa 191-281) of human ERCC1 protein (exact sequence is proprietary)
Target Antigen
ERCC1 | RAD10
Clonality
Monoclonal
Clone
ERCC1/2683
Type
Primary
Source
Animal
Origin
Animal
Positive Control
HeLa, HepG2 cells. Tonsil.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~110 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2683), CF568 conjugate, 0.1mg/mL?

The catalog number for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2683), CF568 conjugate, 0.1mg/mL is BNC682683-500.

What sizes are available for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2683), CF568 conjugate, 0.1mg/mL?

ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2683), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2683), CF568 conjugate, 0.1mg/mL in stock?

ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2683), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2683), CF568 conjugate, 0.1mg/mL?

ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2683), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2683), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2683), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2683), CF568 conjugate, 0.1mg/mL?

The safety data sheet for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2683), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b8061270361e10c445/msds/bnc682683-500.pdf.

What is ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2683), CF568 conjugate, 0.1mg/mL used for?

Recognizes a protein of 110 kDa, identified as Excision Repair Cross Complementing 1 (ERCC1) . It is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae, which is required in mitotic intrachromosomal recomb

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

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