RAD51 (Prognostic and Response to Chemotherapy Marker) (RAD51/2701), CF640R conjugate, 0.1mg/mL

Catalog number BNC402701-100

Price for BNC402701-100

Size / count 1x 100 µL

About this product

RAD51 is one of the key factors of DNA repair by homologous recombination and has been shown to have anti-apoptotic activity in tumor cells. RAD51 protein interacts with a variety of tumor suppressor proteins including p53, BRCA1 and BRCA2. Elevated expression of RAD51 enhances radio-resistance of human tumor cells. Overexpression of RAD51 protein in tumor cells renders them resistant against cytotoxic drugs like Cisplatin. RAD51 interacts with BRCA1 and BRCA2 to influence subcellular localization and cellular response to DNA damage. BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis from deregulation of RAD51. High-level expression of RAD51 has been observed in a variety of human malignancies. RAD51 overexpression correlates with histological grading of the tumor in invasive ductal mammary carcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC402701-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: RCA1/BRCA2 containing complex; subunit 5; BRCC5; DNA repair protein RAD51; FANCR; HsT16930; MRMV2; RAD51; RAD51 recombinase; RAD51A; RECA; RecA like protein; Recombination protein A
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: RAD51
Gene ID: 5888
NCBI Gene ID: 631709
UniProt: Q06609
Swiss Prot: Q06609
Host: Mouse
Species Reactivity: Human
Reactivity: RAD51
Immunogen: Recombinant fragment of human RAD51 protein (around aa 1-134) (exact sequence is proprietary)
Target Antigen: RAD51
Clonality: Monoclonal
Clone: RAD51/2701
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |WB (verified)
Positive Control: K562, HeLa or MCF-7 cells. Colon or breast Carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 37 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for RAD51 (Prognostic and Response to Chemotherapy Marker) (RAD51/2701), CF640R conjugate, 0.1mg/mL?

The catalog number for RAD51 (Prognostic and Response to Chemotherapy Marker) (RAD51/2701), CF640R conjugate, 0.1mg/mL is BNC402701-100.

What sizes are available for RAD51 (Prognostic and Response to Chemotherapy Marker) (RAD51/2701), CF640R conjugate, 0.1mg/mL?

RAD51 (Prognostic and Response to Chemotherapy Marker) (RAD51/2701), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is RAD51 (Prognostic and Response to Chemotherapy Marker) (RAD51/2701), CF640R conjugate, 0.1mg/mL in stock?

RAD51 (Prognostic and Response to Chemotherapy Marker) (RAD51/2701), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures RAD51 (Prognostic and Response to Chemotherapy Marker) (RAD51/2701), CF640R conjugate, 0.1mg/mL?

RAD51 (Prognostic and Response to Chemotherapy Marker) (RAD51/2701), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for RAD51 (Prognostic and Response to Chemotherapy Marker) (RAD51/2701), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for RAD51 (Prognostic and Response to Chemotherapy Marker) (RAD51/2701), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for RAD51 (Prognostic and Response to Chemotherapy Marker) (RAD51/2701), CF640R conjugate, 0.1mg/mL?

The safety data sheet for RAD51 (Prognostic and Response to Chemotherapy Marker) (RAD51/2701), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is RAD51 (Prognostic and Response to Chemotherapy Marker) (RAD51/2701), CF640R conjugate, 0.1mg/mL used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.