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Product details

Tal1 (TAL1/2707), CF640R conjugate, 0.1mg/mL

Catalog number BNC402707-100

Price for BNC402707-100

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Size / count 1x 100 µL

About this product

Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIHLH transcription factors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC402707-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
BHLHa17; Class A basic helix-loop-helix protein 17; OTTHUMP00000009563; OTTHUMP00000009564; SCL; STEM CELL LEUKEMIA HEMATOPOIETIC TRANSCRIPTION FACTOR; Stem cell protein; T cell acute lymphocytic leukemia 1; T cell acute lymphocytic leukemia 1 protein; T cell acute lymphocytic leukemia 1 protein; T cell leukemia/lymphoma 5 protein; T-cell acute lymphocytic leukemia protein 1; T-cell leukemia/lymphoma protein 5; Tal 1 product; TAL 1 protein; TAL bHLH transcription factor 1 erythroid differentiation factor; TAL-1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TAL1
Gene ID
6886
NCBI Gene ID
705618
UniProt
P17542
Swiss Prot
P17542
Host
Mouse
Species Reactivity
Human
Reactivity
Tal1
Immunogen
Recombinant human full-length TAL1 protein
Target Antigen
Tal1
Clonality
Monoclonal
Clone
TAL1/2707
Type
Primary
Source
Animal
Origin
Animal
Positive Control
A549 xenograft.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
42 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for Tal1 (TAL1/2707), CF640R conjugate, 0.1mg/mL?

The catalog number for Tal1 (TAL1/2707), CF640R conjugate, 0.1mg/mL is BNC402707-100.

What sizes are available for Tal1 (TAL1/2707), CF640R conjugate, 0.1mg/mL?

Tal1 (TAL1/2707), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Tal1 (TAL1/2707), CF640R conjugate, 0.1mg/mL in stock?

Tal1 (TAL1/2707), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Tal1 (TAL1/2707), CF640R conjugate, 0.1mg/mL?

Tal1 (TAL1/2707), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Tal1 (TAL1/2707), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Tal1 (TAL1/2707), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Tal1 (TAL1/2707), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Tal1 (TAL1/2707), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Tal1 (TAL1/2707), CF640R conjugate, 0.1mg/mL used for?

Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate e

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

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