• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

CD80 (B7-1) (C80/2723), CF640R conjugate, 0.1mg/mL

Catalog number BNC402723-100

Price for BNC402723-100

Sign In for Pricing

Size / count 1x 100 µL

About this product

T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC402723-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Activation B7-1 antigen; B lymphocyte activation antigen B7; B7; B7-1; BB1; CD28 antigen ligand 1; CD28LG; CD28LG1; CD80; Costimulatory factor CD80; CTLA-4 counter-receptor B7.1; LAB7; T-lymphocyte activation antigen CD80
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD80
Gene ID
941
NCBI Gene ID
838
UniProt
P33681
Swiss Prot
P33681
Host
Mouse
Species Reactivity
Human
Reactivity
CD80
Immunogen
Recombinant fragment of human CD80 protein (around aa 35-142) (exact sequence is proprietary)
Target Antigen
CD80
Clonality
Monoclonal
Clone
C80/2723
Type
Primary
Source
Animal
Origin
Animal
Positive Control
Raji or Ramos Cells. Tonsil, Spleen or Thymus
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
60 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for CD80 (B7-1) (C80/2723), CF640R conjugate, 0.1mg/mL?

The catalog number for CD80 (B7-1) (C80/2723), CF640R conjugate, 0.1mg/mL is BNC402723-100.

What sizes are available for CD80 (B7-1) (C80/2723), CF640R conjugate, 0.1mg/mL?

CD80 (B7-1) (C80/2723), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD80 (B7-1) (C80/2723), CF640R conjugate, 0.1mg/mL in stock?

CD80 (B7-1) (C80/2723), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD80 (B7-1) (C80/2723), CF640R conjugate, 0.1mg/mL?

CD80 (B7-1) (C80/2723), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD80 (B7-1) (C80/2723), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for CD80 (B7-1) (C80/2723), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD80 (B7-1) (C80/2723), CF640R conjugate, 0.1mg/mL?

The safety data sheet for CD80 (B7-1) (C80/2723), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD80 (B7-1) (C80/2723), CF640R conjugate, 0.1mg/mL used for?

T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenti

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

You Might Also Like
CD8 (RIV11), CF555 conjugate, 0.1mg/mL
CD8 (RIV11), CF555 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC550333-500
TNF alpha (J2D10), CF405S conjugate, 0.1mg/mL
TNF alpha (J2D10), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040994-100
CD5 (Cris-1), CF740 conjugate, 0.1mg/mL
CD5 (Cris-1), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740176-500
Cytokeratin 10 (KRT10/844), CF488A conjugate, 0.1mg/mL
Cytokeratin 10 (KRT10/844), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880844-500
Vimentin (VM1170), CF647 conjugate, 0.1mg/mL
Vimentin (VM1170), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC471170-500
CD27 (Tumor Necrosis Factor Receptor Superfamily 7) (rLPFS2/1611), CF405S conjugate, 0.1mg/mL
CD27 (Tumor Necrosis Factor Receptor Superfamily 7) (rLPFS2/1611), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC041976-500
MCM7 (Proliferation Marker) (MCM7/1468), CF568 conjugate, 0.1mg/mL
MCM7 (Proliferation Marker) (MCM7/1468), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC681468-500
Moesin (MSN/492), CF405S conjugate, 0.1mg/mL
Moesin (MSN/492), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040492-500