CD80 (B7-1) (C80/2723), CF647 conjugate, 0.1mg/mL

Catalog number BNC472723-500

Price for BNC472723-500

Size / count 1x 500 µL

About this product

T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472723-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Activation B7-1 antigen; B lymphocyte activation antigen B7; B7; B7-1; BB1; CD28 antigen ligand 1; CD28LG; CD28LG1; CD80; Costimulatory factor CD80; CTLA-4 counter-receptor B7.1; LAB7; T-lymphocyte activation antigen CD80
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD80
Gene ID: 941
NCBI Gene ID: 838
UniProt: P33681
Swiss Prot: P33681
Host: Mouse
Species Reactivity: Human
Reactivity: CD80
Immunogen: Recombinant fragment of human CD80 protein (around aa 35-142) (exact sequence is proprietary)
Target Antigen: CD80
Clonality: Monoclonal
Clone: C80/2723
Type: Primary
Source: Animal
Origin: Animal
Positive Control: Raji or Ramos Cells. Tonsil, Spleen or Thymus
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 60 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for CD80 (B7-1) (C80/2723), CF647 conjugate, 0.1mg/mL?

The catalog number for CD80 (B7-1) (C80/2723), CF647 conjugate, 0.1mg/mL is BNC472723-500.

What sizes are available for CD80 (B7-1) (C80/2723), CF647 conjugate, 0.1mg/mL?

CD80 (B7-1) (C80/2723), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD80 (B7-1) (C80/2723), CF647 conjugate, 0.1mg/mL in stock?

CD80 (B7-1) (C80/2723), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD80 (B7-1) (C80/2723), CF647 conjugate, 0.1mg/mL?

CD80 (B7-1) (C80/2723), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD80 (B7-1) (C80/2723), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for CD80 (B7-1) (C80/2723), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD80 (B7-1) (C80/2723), CF647 conjugate, 0.1mg/mL?

The safety data sheet for CD80 (B7-1) (C80/2723), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02af061270361e1091d1/msds/bnc472723-500.pdf.

What is CD80 (B7-1) (C80/2723), CF647 conjugate, 0.1mg/mL used for?

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.