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Product details

CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF640R conjugate, 0.1mg/mL

Catalog number BNC402749-100

Price for BNC402749-100

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Size / count 1x 100 µL

About this product

DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC402749-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD209; CDSIGN; CIRE; CLEC4L; DC-SIGN; DC-SIGN1; DCSIGN; Dendritic cell-specific ICAM-3 Grabbing Non-integrin 1; HIV GP120 Binding Protein; SIGN-R1; SIGNR5
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD209
Gene ID
30835
NCBI Gene ID
278694
UniProt
Q9NNX6
Swiss Prot
Q9NNX6
Host
Rabbit
Species Reactivity
Human
Reactivity
CD209|DC-SIGN
Immunogen
Recombinant full-length human CD209 protein
Target Antigen
CD209 | DC-SIGN
Clonality
Recombinant Monoclonal
Clone
C209/2749R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
THP-1 or HeLa cells (IF/FACS). Human liver or spleen lysate (WB). Human small intestine (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
45 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF640R conjugate, 0.1mg/mL?

The catalog number for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF640R conjugate, 0.1mg/mL is BNC402749-100.

What sizes are available for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF640R conjugate, 0.1mg/mL?

CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF640R conjugate, 0.1mg/mL in stock?

CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF640R conjugate, 0.1mg/mL?

CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF640R conjugate, 0.1mg/mL?

The safety data sheet for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF640R conjugate, 0.1mg/mL used for?

DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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