CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2749-100

Price for BNCB2749-100

Size / count 1x 100 µL

About this product

DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB2749-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD209; CDSIGN; CIRE; CLEC4L; DC-SIGN; DC-SIGN1; DCSIGN; Dendritic cell-specific ICAM-3 Grabbing Non-integrin 1; HIV GP120 Binding Protein; SIGN-R1; SIGNR5
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD209
Gene ID: 30835
NCBI Gene ID: 278694
UniProt: Q9NNX6
Swiss Prot: Q9NNX6
Host: Rabbit
Species Reactivity: Human
Reactivity: CD209|DC-SIGN
Immunogen: Recombinant full-length human CD209 protein
Target Antigen: CD209 | DC-SIGN
Clonality: Recombinant Monoclonal
Clone: C209/2749R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: THP-1 or HeLa cells (IF/FACS). Human liver or spleen lysate (WB). Human small intestine (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 45 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), Biotin conjugate, 0.1mg/mL?

The catalog number for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), Biotin conjugate, 0.1mg/mL is BNCB2749-100.

What sizes are available for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), Biotin conjugate, 0.1mg/mL?

CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), Biotin conjugate, 0.1mg/mL in stock?

CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), Biotin conjugate, 0.1mg/mL?

CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), Biotin conjugate, 0.1mg/mL?

The safety data sheet for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), Biotin conjugate, 0.1mg/mL used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.